CHAPTER TWO: TOXICOLOGIC RESEARCH AND INFORMATION DISSEMINATION
Table 2.
Number of Sites with a Hazardous Substance in a Completed
Exposure Pathway
Substance Name
All Sites
NPL Sites
Lead
298
206
Trichloroethylene
277
239
215
147
Tetrachloroethylene
206
167
Benzene
149
116
Cadmium
148
105
146
102
Polychlorinated biphenyls
130
96
1,1,1-Trichloroethane
116
97
Zinc
116
75
PREPARATION OF TOXICOLOGICAL PROFILES
CERCLA, as amended, requires ATSDR to prepare toxicological profiles that
examine each hazardous substance on the CERCLA Priority List of Hazardous
Substances. These profiles summarize the current scientific literature and
interpret available toxicologic and epidemiologic information to determine
levels of significant human exposure for the substance.
ATSDR also provides toxicological profiles at the request of the U.S.
Department of Defense (DOD) and the U.S. Department of Energy (DOE).
During FY 1999, ATSDR personnel developed or updated 44 draft or final
versions of toxicological profiles. These profiles covered CERCLA substances
and non-CERCLA substances identified by DOD and DOE. (See Appendix B
for a list of toxicological profiles completed in FY 1999.)
CERCLA
In FY 1999, ATSDR published 20 updated or new toxicological profiles (see
Appendix B). Eight toxicological profiles underwent public-comment review,
after which relevant information identified during the review process was
incorporated. These profiles will be published in final form in FY 2000. Eight
toxicological profiles under development during FY 1999 will be distributed for
a 90-day public-comment period.
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