Public Health Assessment Public Comment Release
Because of uncertainties involved in estimating carcinogenic risk, ATSDR employs a weight-of-
evidence approach in
evaluating all relevant data.3 Therefore, the carcinogenic risk is
described
in words (qualitatively) rather than giving a numerical risk estimate only. The numerical risk
estimate must be considered in the context of the variables and assumptions involved in their
derivation and in the broader context of biomedical opinion, host factors, and actual exposure
conditions. The actual parameters of environmental exposures must be given careful
consideration in
evaluating the assumptions and variables relating to
both toxicity and exposure.
26